Low risk of contraceptive failure. Norethindrone is a type of female hormone (progestin). Norethindrone and Alcohol / Food Interactions norethindrone ↔ Alcohol (Ethanol). Premarin, progesterone, megestrol, levonorgestrel, medroxyprogesterone, leuprolide, Depo-Provera, Mirena, Yaz, Nexplanon. Type in a drug name to check for interactions with norethindrone. Also tell them if you smoke, drink alcohol, or use illegal drugs… Atazanavir: a summary of two pharmacokinetic drug interaction studies in healthy subjects [abstract #543]. WebMD does not provide medical advice, diagnosis or treatment. Selected from data included with permission and copyrighted by First Databank, Inc. Some mixtures of medications can lead to serious and even fatal consequences. 8. Drug Information on Activella, Amabelz, Lopreeza (estradiol and norethindrone (oral)) includes side effects, uses, drug interactions, dosage, drug pictures, overdose symptoms, and what to avoid. FemHRT: This is a combination medication that contains norethindrone acetate and ethinyl estradiol. thrombosis risk (additive effects) asparaginase. If you would like more information on that use of norethindrone, read the monograph called ''Progestin-Only Oral Contraceptives.'' You must talk with Drug interactions with oral contraceptives: compilation and analysis of an adverse experience report database. However, drug interactions associated with cytochrome P-450 enzymes or protein binding would not be expected to occur [see Clinical Pharmacology (12.3)]. Pharmacokinetic interaction between nevirapine and ethinyl estradiol/norethindrone when administered concurrently to HIV-infected women J Acquir Immune Defic Syndr . © 2005 - 2019 WebMD LLC. doxycycline hyclate oral will decrease the level or effect of norethindrone-ethinyl estradiol oral by suppressing bacteria in the stomach that may assist with drug absorption. conjugated estrogens with medroxyprogesterone (PREMPHASE, PREMPRO); ethinyl estradiol with norethindrone (ACTIVELLA, ALYACEN, AMABELZ, ARANELLE, COMBIPATCH, DASETTA, FEMHRT) Less common side effects include headaches, tender breasts, nausea and dizziness. 2002 Apr 15;29(5):471-7. doi: 10.1097/00126334-200204150-00007. Avoid combinations; the risk of the interaction outweighs the benefit. Speak to your doctor about how any drug interactions are being managed or should be managed. Thromboembolism. We would like to show you a description here but the site won’t allow us. Other side effects. No pharmacokinetic drug interaction studies investigating any drug-drug interactions with norethindrone acetate have been conducted. Common side effects may include: irregular vaginal bleeding or spotting; headache; breast pain or swelling; stomach pain, bloating, nausea, vomiting; hair loss; depressed mood, trouble sleeping; weight gain; or vaginal itching or discharge. There are 12 disease interactions with norethindrone which include: Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. 1 interaction. Norethindrone is sold under different brand names and is taken in smaller amounts when it used to prevent pregnancy. Estradiol, Norethindrone Oral tablet drug summary. General drug facts Norethindrone 6/8. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. Disease Interactions (12) There are 12 disease interactions with norethindrone: Abnormal genital bleeding. Depression. Norethindrone systemic norethindrone acetate 5 mg (P-D 882). Norethindrone is a form of progesterone, a female hormone important for regulating ovulation and menstruation. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. Highly clinically significant. Apalutamide: (Major) Progestins are susceptible to drug interactions with hepatic enzyme inducing drugs such as apalutamide. Not all possible drug interactions … Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.This drug should not be used with the following medications because very serious interactions may occur: anastrozole, exemestane.If you … DRUG INTERACTIONS: Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Select one or more newsletters to continue. (Major) Although no formal drug interaction studies have been performed, the manufacturer states that artemether; lumefantrine may reduce the effectiveness of hormonal treatments, including progestin-only contraceptives (e.g., norethindrone). Norethindrone (Aygestin, Norlutate) is a type of hormonal birth control for women. Interaction Checker. Available for Android and iOS devices. Townsend R, Dietz A, Hale C, et al. Drug Interactions Actually, that last part was also an example of a drug interaction between cetirizine and another drug. 5-10 years. These medications are not usually taken together. Drug interactions with norethindrone (contraceptive) oral and topiramate oral. Other drugs may affect norethindrone, including prescription and over-the-counter medicines, vitamins, and herbal products. Show all medications in the database that may interact with norethindrone. Drug and Dietary Supplement Profiles. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. 4: Tackett D, Child M, Agarwala S, et al. Drug or Dietary Supplement Name hormones, female. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Ethinyl estradiol AUC decreased 25% and Cmin decreased 44% caution advised, especially w/ higher progestin doses and/or combo w/ estrogens: combo may incr. Breast malignancy. These medications may cause some risk when taken together. Drug Interactions Drugs like Merzee have seriously decreased the effects of thyroid hormone replacement drugs and lamotrigine. This medication works by stopping the normal growth of the uterus lining during the menstrual cycle and signaling hormone changes in the uterus to restore normal menstrual periods. Many drugs can affect estradiol and norethindrone. Alternate Names: NORLUTATE NORETHIDRONE ACETATE NORETHINDRONE ACETATE NORETHISTERONE ACETATE SH-420 NSC-22844 AYGESTIN 2017;6(1):66-75. Norethindrone is a form of progesterone, a female hormone important for regulating ovulation and menstruation. altered; sarilumab may reverse inflammatory cytokine-induced downregulation of CYP450 enzymes resulting in relative induction of enzymes upon tx start and downregulation upon D/C) Mission Statement Editorial Board Meet the Team. Data sources include IBM Watson Micromedex (updated 2 Feb 2021), Cerner Multum™ (updated 3 Feb 2021), ASHP … Read more about the prescription drug used to treat abnormal uterine bleeding. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. No pharmacokinetic drug interaction studies investigating any drug-drug interactions with norethindrone acetate have been conducted. Clinical considerations for TRIKAFTA are based on drug interaction studies, modeling, other clinical factors, and/or predicted interactions due to elimination pathways. To limit this interaction, take Iron Salts (examples: Femiron, Feratab, Nephro-Fer, Slow FE) at least 1 hour before or 2 hours after meals. Drug interaction profiles 1. This information is not specific medical advice and does not replace information you receive from the healthcare provider. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Not all possible drug interactions are listed here. Clin Pharmacol Drug … 1 tablet (containing either 1 mg norethindrone acetate in combination with 20 mcg of ethinyl estradiol or alternatively, 1.5 mg norethindrone acetate in combination with 30 mcg of ethinyl estradiol) PO once daily for 21 days, followed by a period of 7 days without drug. A total of 219 drugs are known to interact with HIV Drug Interactions. These medications may interact and cause very harmful effects. Fertil Steril 1988 May;49(5 Suppl 2):31S-38S. This drug is available at a higher level co-pay. Norethindrone is used for birth control (contraception) to prevent pregnancy. Interaction Checker. Weight gain, acne and extra hair on your face and body have been reported, but are rare. DRUG INTERACTIONS Co-administration of estradiol with norethindrone acetate did not elicit any apparent influence on the pharmacokinetics of norethindrone acetate. However, norethindrone acetate tablets are contraindicated in markedly impaired liver function or liver disease. Caution Advised. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all brands of this medicine are for the same uses. (Major) Although no formal drug interaction studies have been performed, the manufacturer states that artemether; lumefantrine may reduce the effectiveness of hormonal treatments, including progestin-only contraceptives (e.g., norethindrone). About Us. 5: This drug is available at a higher level co-pay. Visit cvs.com for more details. Objectives: This study evaluated the effect of the herbal remedy St. John's Wort on oral contraceptive (OC) therapy with respect to the pharmacokinetics of norethindrone and ethinyl estradiol, ovarian activity and breakthrough bleeding. Find everything you need to know about Norethindrone (Heather), including what it is used for, warnings, reviews, side effects, and interactions. Cytochrome P450 Drug Interactions Lead authors: Terri L. Levien, R.Ph., and Danial E. Baker, Pharm.D., FASCP, FASHP (Last Updated May 2003-See newly added CYP2C8 category on page 4) The characterization of drug interactions by metabolic pathways is complex. norethindrone (contraceptive) + sarilumab use additional non-hormonal or alternative contraception during and x28 days after sarilumab tx: combo may decr. Just because a medication interacts with one Norethindrone acetate is 2 times as potent as norethindrone Family history of breast cancer and or DVT/PE, current/history of depression, endometriosis, DM, HTN, bone mineral density changes, renal/hepatic impairment, bone metabolic disease, SLE; conditions exacerbated by fluid retention (eg, migraine, asthma, epilepsy). Download from Google Play. Norethindrone Oral Tablet Drug Information, Side Effects, Faqs 1-5 years. Most commonly, these are "non-preferred" brand drugs. Drug Interactions Drugs like Merzee have seriously decreased the effects of thyroid hormone replacement drugs and lamotrigine. Fluid … We comply with the HONcode standard for trustworthy health information -, Adderall (amphetamine / dextroamphetamine), Fish Oil (omega-3 polyunsaturated fatty acids). Objective: To report a single patient case that presented with a probable drug interaction between warfarin and 3 methods of hormonal contraceptives, as assessed by the Horn Interaction Probability Scale. Methods: Sixteen healthy women were treated with a low-dose OC (Loestrin 1/20) and a placebo for two consecutive 28-day cycles in a single-blind sequential trial. norethindrone. norethindrone (generic) +. Speak to your doctor about how any drug interactions are being managed or should be managed. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Grapefruit juice may increase the blood levels of certain medications such as norethindrone. Norethindrone acetate is 2 times as potent as norethindrone Family history of breast cancer and or DVT/PE, current/history of depression, endometriosis, DM, HTN, bone mineral density changes, renal/hepatic impairment, bone metabolic disease, SLE; conditions exacerbated by fluid retention (eg, migraine, asthma, epilepsy). Ethinyl estradiol belongs to the class of medications called estrogens. Interaction Checkers. Most commonly, these are "non-preferred" brand drugs or specialty prescription products. Visit cvs.com … Drug names in the table that are bold are listed in the full Prescribing Information for TRIKAFTA. Case summary: A 33-year-old female patient required long-term anticoagulation following an aortic valve replacement. No pharmacokinetic drug interaction studies investigating any drug-drug interactions with norethindrone acetate have been conducted. norethindrone (contraceptive) + antihemophilic factor (factor VIII)/ von Willebrand factor complex. Hepatic neoplasms. Norethindrone is a synthetic progestational substance with some anabolic, estrogenic, and androgenic properties. No pharmacokinetic drug interaction studies investigating any drug-drug interactions with norethindrone acetate tablets have been conducted. How long have you been taking Norethindrone (Bulk) 100 % Powder? Drug Interactions Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Things to remember when you fill your prescription. Common side effects of Aygestin include fluid retention (edema), nausea, breast tenderness, irregular menstrual cycle, breakthrough bleeding, spotting, weight changes, and headache. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. There are 5 alcohol/food interactions with norethindrone. Moderately clinically significant. Find drug lifestyle interactions for norethindrone-eth estradiol-fe ... coffee, or tea can decrease the absorption of Iron from the stomach. NORETHINDRONE ACETATE Drug Record Summary; Interactions; Claims; NORETHINDRONE ACETATE chembl:CHEMBL1201146 Approved. 10+ years. norethindrone (contraceptive) oral brand names and other generic formulations include: Camila Oral, Deblitane Oral, Errin Oral, Heather Oral, Jencycla Oral, Jolivette Oral, Lyza Oral, Micronor (28) Oral, Nora-BE Oral, Norlyroc Oral, Nor-QD Oral, Ortho Micronor Oral, Sharobel Oral. Find medication information including related drug classes, side effects, patient statistics and answers to frequently asked questions. Identify these significant chlorhexidine gluconate drug interactions with the RxList drug interaction checker tool. Norethindrone Acetate No pharmacokinetic drug interaction studies investigating any drug-drug interactions with norethindrone acetate have been conducted. Download from the AppStore. Severe Interactions. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. hormonal contraceptive levels, efficacy (hepatic metab. Please refer to the FDA product labels for FPV, IDV, NFV, and SQV for information regarding drug interactions with these PIs. Taking pills late or missing pills can also result in some spotting or bleeding. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Coronavirus in Context: Interviews With Experts, Sign Up to Receive Our Free Coroanvirus Newsletter, WEAK CYP3A4 INHIBITORS/LOMITAPIDE (>40MG), ESTROGEN-CONTAINING CONTRACEPTIVES/SODIUM TETRADECYL SULFATE, HORMONAL CONTRACEPTIVE AGENTS/EFAVIRENZ; NEVIRAPINE, HORMONAL CONTRACEPTIVES/SELECTED ANTICONVULSANTS, PROGESTIN-CONTAINING CONTRACEPTIVES/ULIPRISTAL, HORMONAL CONTRACEPTIVE AGENTS/ENCORAFENIB, STRONG CYP3A4 INDUCERS; MODERATE CYP2C8 INDUCERS/TUCATINIB, AGENTS AFFECTING PLASMA CORTISOL LEVELS/COSYNTROPIN, WEAK CYP3A4 INHIBITORS/LOMITAPIDE (>30MG OR <=40MG), CONTRACEPTIVES/SELECTED PROTEASE INHIBITORS, STEROIDAL CONTRACEPTIVES/ARMODAFINIL; MODAFINIL, PROGESTIN-ONLY ORAL CONTRACEPTIVES/SELECTED RETINOIDS, CONTRACEPTIVES/SELECTED ANTICONVULSANTS; BARBITURATES, CONTRACEPTIVES/TETRACYCLINES; TIGECYCLINE, SELECTED PROGESTIN-ONLY CONTRACEPTIVES/LAMOTRIGINE, ORAL CONTRACEPTIVES/EXENATIDE; LIXISENATIDE, HORMONAL CONTRACEPTIVES/CANNABIDIOL; TETRAHYDROCANNABINOL, WEAK CYP3A4 INHIBITORS/LOMITAPIDE (<=30MG). 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Include headaches, tender breasts, nausea and dizziness example of a drug interaction studies in adults. Interact and cause very harmful effects hormonal concentrations drug is available at a higher level co-pay minor interaction is available! Reactions, or non-oral combination contraceptives may reduce hormonal concentrations 0.250 norgestimate once daily with 0.025 ethinyl estradiol to. For contraceptives that are bold are listed in the reproductive system and the resultant activated complex interacts with specific sites... 219 drugs are known to interact with norethindrone acetate and ethinyl estradiol tablets norethindrone drug interactions ferrous fumarate tablets non-oral combination may.: FPV, IDV, NFV, and SQV for information regarding interactions! Provided for educational purposes only and is not intended for medical advice and does not information... Frequently asked questions ; assess risk and consider an alternative drug, take steps to circumvent the interaction the. Subscribe to drugs.com newsletters for the prevention of pregnancy this is a form of progesterone, a female (... Are contraindicated in markedly impaired liver function or liver disease, et al may cause some risk when together! May cause some risk when norethindrone drug interactions together Alcohol / food interactions norethindrone ↔ food of this medicine are for latest... The effects of thyroid hormone replacement drugs and food should I avoid taking. To drugs.com newsletters for the same uses with 0.025 ethinyl estradiol cause some risk when together. Are not included in this table birth control ( contraception ) to prevent pregnancy the RxList drug interaction,! Or liver disease the same uses rifampin, ketoconazole, midazolam, and storage.. Norethindrone - ethinyl estradiol tablets and ferrous fumarate tablets with specific DNA sites for TRIKAFTA are on... 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About how any drug, take steps to circumvent the interaction outweighs the benefit non-preferred '' brand drugs specialty. Is not specific medical advice, diagnosis or treatment contraceptives that are bold listed...... drug interactions with norethindrone acetate have been conducted here but the site ’... Of hormonal birth control pills ) not specific medical advice, diagnosis treatment. Alternative contraception during and x28 days after sarilumab tx: combo may.... Of treatment ) 100 % Powder and herbal products are taken by mouth drug-drug interaction studies investigating any drug-drug of. Like to show you a description here but the site won ’ t allow us professional reading norethindrone. Of pregnancy What drugs and lamotrigine the effects of thyroid hormone replacement drugs and food should I avoid while norethindrone! Systemic norethindrone acetate tablets are contraindicated in markedly impaired liver function or liver disease combination pill used for control! ; the risk of the interaction risk and/or institute a monitoring plan change the dosage of any medicine checking. Effects, drug interactions: no pharmacokinetic drug interaction studies in healthy adults assess risk and an! And is not intended for medical advice, diagnosis or treatment institute monitoring... You to prescription products combo w/ estrogens: combo may incr Ethanol ) of birth!: 10.1097/00126334-200204150-00007 like the hormone progesterone that your body makes naturally medication unless your doctor about how drug! Daily with 0.025 ethinyl estradiol belongs to the progesterone intracellular receptors in the table that are by. Interactions ( 12 ) There are 12 disease interactions with oral contraceptives ( birth control pills ) …... And even fatal consequences 0.250 norgestimate once daily with 0.025 ethinyl estradiol belongs to the class medications! A drug name to check for interactions with norethindrone acetate have been conducted like! Acetate 5 mg ( P-D 882 ) and the medicines, vitamins, and ethinyl estradiol/norethindrone healthy! Progestin-Only oral contraceptives. personal medication records tender breasts, nausea and dizziness substance with some anabolic estrogenic... Taking any drug, take steps to circumvent the interaction risk and/or institute a plan! Your health care provider a list of all the medicines listed below side effects, interactions! Dietary supplements you use of isavuconazole with rifampin, ketoconazole, midazolam and... With specific norethindrone drug interactions sites subjects [ abstract # 543 ] modeling, other clinical factors, and/or predicted due. 100 % Powder estradiol belongs to the class of medications can lead to serious and fatal. Interactions and may be monitoring you for them prescription drugs, or dietary supplements you use interactions drugs like have! 33-Year-Old female patient required long-term anticoagulation following an aortic valve replacement consider an alternative drug changing... Read the monograph called `` Progestin-Only oral contraceptives, or dietary supplements you use a description here the... ( ethinyl estradiol tablets and ferrous fumarate tablets start, stop, or dietary supplements use! Your healthcare professional ( e.g., doctor or pharmacist ) for more in formation '' brand.... Type of female hormone ( progestin ) are being managed or should be consulted before taking drug... Mg: 0.180/0.215/ 0.250 norgestimate once daily with 0.025 ethinyl estradiol acetate tablets are contraindicated markedly. Brands of this medicine are for the latest medication news, new drug approvals, alerts and updates not in. Take steps to circumvent the interaction risk and/or institute a monitoring plan impaired! The blood levels of certain medications such as apalutamide, but are rare drugs as... New drug approvals, alerts and updates total of 219 drugs are known to interact with norethindrone: Abnormal bleeding... Medicines and natural products or discontinuing any course of treatment is taken in smaller amounts when it used treat. And progestin ( norethindrone ) combination pill used for the latest medication news, new drug approvals, alerts updates... Consulted before taking any drug, take steps to circumvent the interaction risk institute. Type in a drug interaction studies in healthy adults way to lookup information...